The term “herbal drugs” denotes plants or plant parts that have been converted into phytopharmaceuticals. The quality control standards of various medicinal plants used in indigenous system of medicine are becoming more relevant today in view of commercialization of formulations based on medicinal plants. For standardization and quality assurance purposes, following three attributes are desirable i) Authenticity ii) Purity and iii) Assay. Authenticity relates to proving that the material is true. Authentication in itself involves many parameters including gross morphology, microscopy, chemical, physical, biological and toxicological analysis. Assay part of standardization is chemical and biological profiling which could assess the chemical effects and curative values. The new era of herbal drug standardization includes chemometrics, Gel Electroporesis, Metabolomic technique, Differenital pluse polarography combination of this all techniques show clear picture and this will help to introduce new molecule or formulation in society which will safe and effective one